The new MicroNIR PAT-U process spectrometer is a spectrometer innovation from the company. It is a scalable, sturdy next-generation system for real-time process monitoring in pharmaceutical and food process analytical technology (PAT) applications. With proven Viavi linear variable filter (LVF) technology, the PAT-U is recognized to have the smallest form factor on the market in a fit-for-purpose design. This makes it ideal for application with processing equipment of all sizes, with stability and the performance to facilitate efficient manufacturing.
The MicroNIR PAT-U can be used in an easy manner and was designed for the present-day demanding GMP-regulated environments; however it still needs marginal system maintenance. There are no moving components or expensive fiber optic cables, enabling excellent instrument stability and performance in challenging process environments. Its stainless steel exterior is water and dust resistant according to IP65 standards and cleans easily.
The key features of the new MicroNIR PAT-U process spectrometer are listed below:
- Compact for effortless integration
- USB communication
- Non-invasive, real-time NIR analysis
- Washable, IP67 rated enclosure
The main applications of the new MicroNIR PAT-U process spectrometer are listed below:
- Pharmaceutical manufacturing
- Fluid bed drying
- Content uniformity
- Food and feed manufacturing
- Moisture content
- Nutritional assay
- Industrial processing
- Reaction monitoring
The software package allows deployment flexibility from process/product development to manufacturing environments and offers encrypted secure data storage, audit trails, comprehensive user management and numerous other capabilities required for regulated GMP environments.
- The instrument control software enables uncomplicated data acquisition, user management, real-time analysis, method development, method investigation, and instrument qualification per USP 1119 criteria
- The Viavi Unscrambler® X Lite regression and classification software provides a full set of chemometric tools for data investigation and calibration model development
- The MicroNIR Process software is programmed for easy process monitoring of varied process techniques from a variety of MicroNIR spectrometers. Process engineers can smoothly view acquired data and trend results in real-time with concurrent output of key process data to the plant control system.
Mounting and Process Integration
The MicroNIR PAT-U is engineered to guarantee highest flexibility to meet the many varied criteria for process integration. It adds into a process with different mounts.
The standard mount includes a weld in base flange, a 2” sanitary (hygienic) flange mount, a sapphire window, and a retaining ring with O-rings. The base flange is welded into a hole cut in the specific process equipment. Next, the window, the sanitary flange mount, and retaining ring are assembled. The PAT-U with a modifiable collet then secures against a sanitary flange and the window using a standard tri-clover clamp (or C-clamp). All pieces can be dismantled for easy cleaning and maintenance.
The threaded mount allows a user to weld a mount into the process equipment and then link the PAT-U using the threaded tip of the spectrometer. This mount also has a removable window to allow easy cleaning and maintenance.
Two integrated vacuum tungsten lamps
Flood illumination/ 0° observer
Input aperture dimensions
2.5 x 3.0 mm
Sample working distance
0 – 15 mm from window
Linear variable filter
128-pixel InGaAs photodiode array
30 µm x 250 µm/50 µm
950 – 1650 nm (10,526 – 6060 cm-1)
6.2 nm for 950 – 1650 nm
Spectral bandwidth (FWHM)
<1.25% of center wavelength (1% typical) (for example, @1000 nm, resolution is <12.5 nm)
Dynamic range (Max)
Measurement time (typical)
0.25 – 0.5 second
10 ms typical, minimum 10 µsec, maximum limited by dark signal
318 g (11.2 oz)
45 mm diameter x 69 mm tall
USB powered (<500 mA @5V)
Encrypted, Unsb, CSV, and SPC output
Windows 8.1, 8, and 7
MicroNIR Pro standard, Unscrambler X Lite, MicroNIR Process
0 – 40 deg C (non-condensing)
Stainless steel 316: dust and waterproof, sealed and cleanable to IP67 standard
Adaptable stainless steel tri-clover mount, screw into welded flange